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A recipe for proteomics diagnostic test development: the OVA1 test, from biomarker discovery to FDA clearance.
Although diagnostic test development remains challenging, novel technologies, including proteomics, genomics, and microRNA analysis, provide opportunities to identify biomarkers that in principle could accelerate the development of new diagnostic tests. Unfortunately, the literature is littered with initial biomarker discoveries that have failed to reach the clinic. We sought to identify a reci...
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ژورنال
عنوان ژورنال: Nature
سال: 2019
ISSN: 0028-0836,1476-4687
DOI: 10.1038/d41586-019-00153-6